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pentobarbital will lessen the level or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital will lessen the level or result of budesonide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.Human info. In a very 29-12 months epidemiological examine of 9,136 in